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K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
InChi: InChI=1S/C20H19N7/c1-25-12-16(10-23-25)7-8-27-14-22-19(18-11-24-26(2)13-18)20(27)17-5-3-15(9-21)4-6-17/h3-6
In vivo administration of LY-2157299 ameliorated anemia in a TGF-β overexpressing transgenic mouse model of bone marrow failure
cytokine production and autoantibody levels at well-tolerated doses
TUG-770 - CAS# 1402601-82-4 428 K-Ras(G12C) inhibitors allosterically control GTPTUG 770, CAS No. 1402601 82 4, is a Highly Potent Free Fatty Acid Receptor 1 (FFA1 GPR40) Agonist for Treatment of Type 2 Diabetes. Free fatty acid receptor 1 (FFA1 or GPR40) enhances glucose stimulated insulin secretion from pancreatic cells and currently attracts high interest as a new target for the treatment of type 2 diabetes. Product information CAS Number: 1402601 82 4 Molecular Weight: 307. 32 Formula: C19H14FNO2 Synonym: TUG 770 TUG770 TUG
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