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attenuates the development of compensatory right ventricular hypertrophy
with treatment resulting in marked increases in periosteal bone formation and cortical thickness in ovariectomized monkeys whereas trabecular bone formation is reduced
SR-59230A oxalate
BACE-1 inhibitor 2 6780 At this time pointBACE 1 inhibitor 2 is a potent and CNS permeable BACE 1 inhibitor with an IC50 of 1. 5 nM in BACE 1 enzymatic assay. Product information Molecular Weight: 467. 42 Formula: C21H21F4N5O3 Chemical Name: N [3 [(4aS, 6S, 8aS) 2 amino 3, 3 difluoro 6 methyl 4a, 5, 6, 8 tetrahydro 4H pyrano[3, 4 b]pyridin 8a yl] 4 fluorophenyl] 5 (fluoromethoxy)pyrazine 2 carboxamide Smiles: C[C@H]1C[C@H]2CC(F)(F)C(N)=N[C@]2(CO1)C1=CC(=CC=C1F)NC(=O)C1=CN=C(C=N1)OCF InChiKey:
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