IDO-IN-9 1188 Smiles: [2H]C1([2H])N(C2=NSC3C=CC=CC=32)C([2H])([2H])C([2H])([2H])N(C[C@@H]2CCCC[C@H]2CN2C(=O)[C@@H]3[C@@H]([C@@H]4C[C@H]3C[C@H]4O)C2=O)C1([2H])[2H]

Smiles: [2H]C1([2H])N(C2=NSC3C=CC=CC=32)C([2H])([2H])C([2H])([2H])N(C[C@@H]2CCCC[C@H]2CN2C(=O)[C@@H]3[C@@H]([C@@H]4C[C@H]3C[C@H]4O)C2=O)C1([2H])[2H]

PF-06700841 inhibits EPO/pSTAT5 (JAK2 homodimer) in HWB spiked with CD34+ progenitor cells (IC50 of 577 nM)

0% and 0% of the control (n=5

InChiKey: DVUFPRMEKXKECP-UHFFFAOYSA-N

IDO-IN-9 1188 Smiles: [2H]C1([2H])N(C2=NSC3C=CC=CC=32)C([2H])([2H])C([2H])([2H])N(C[C@@H]2CCCC[C@H]2CN2C(=O)[C@@H]3[C@@H]([C@@H]4C[C@H]3C[C@H]4O)C2=O)C1([2H])[2H]IDO IN 9 is an indoleamine 2,3 dioxygenase (IDO) inhibitor with IC50s of 0. 011 M (Kinase) and 0. 0018 M (Hela Cell), extracted from patent WO 2016041489 A1, compound 6. Product information CAS Number: 1888378 12 8 Molecular Weight: 446. 25 Formula: C13H13BrFN7O3S Chemical Name: (Z) N (3 bromo 4 fluorophenyl) 4 ({2 [(cyanoimino)(methyl)oxo sulfanyl]ethyl}amino) N' hydroxy 1,2,5 oxadiazole 3 carboximidamide Smiles: CS(=O)(CCNC1=NON=C1 C(