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GNE 5729 imus PubMed PMID: 29193663

SKU: 78118355876

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Description

PubMed PMID: 29193663

36-/m0/s1/i4+1D3

Solubility: DMSO: 53 mg/mL(198

GNE 5729 imus PubMed PMID: 29193663GNE 5729 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 37 nM for GluN2A, 4. 7 and 9. 5 M for GluN2C and GluN2D, respectively. Product information CAS Number: 2026635 66 3 Molecular Weight: 428. 20 Formula: C17H10Cl2F3N5O Chemical Name: (1R,2R) 2 (7 chloro 2 {[5 chloro 3 (trifluoromethyl) 1H pyrazol 1 yl]methyl} 4 oxo 4H pyrido[1,2 a]pyrimidin 6 yl)cyclopropane 1 carbonitrile Smiles:

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