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Pharmacodynamic study is performed using Del19/T790M/C797S_NIH3T3 xenografted tumors in mice
Bleomycin is administered in 50 μL of DMSO intraperitoneally
Eflornithine irreversibly inhibits ornithine decarboxylase
CAS Number: 548472-68-0
AD80 stone Methyltransferase Pharmacodynamic study is performed usingAD80, a multikinase inhibitor, inhibits RET, RAF,SRCand S6K, with greatly reduced mTOR activity. Product information CAS Number: 1384071 99 1 Molecular Weight: 473. 43 Formula: C22H19F4N7O Chemical Name: 3 {4 [4 amino 1 (propan 2 yl) 1H pyrazolo[3,4 d]pyrimidin 3 yl]phenyl} 1 [2 fluoro 5 (trifluoromethyl)phenyl]urea Smiles: CC(C)N1N=C(C2=C(N)N=CN=C12)C1C=CC(=CC=1)NC(=O)NC1=CC(=CC=C1F)C(F)(F)F InChiKey: CYORWDWRQMVGHN UHFFFAOYSA N InChi: InChI=1S
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