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Raloxifene 6-glucuronide Catalog No.:M13237-10 Hippo coactivator YAP1 upregulates SOX9

SKU: 73603439344

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Description

Hippo coactivator YAP1 upregulates SOX9 and endows esophageal cancer cells with stem-like properties

48 hours) treatment markedly suppresses the expression of vascular endothelial (VE)-cadherin in a dose-dependent manner and also slightly diminishes the expression of Sema4D in C8161 cells

11-dihydroxy-3

Smiles: ONC(=O)CCC1=CC=C(CN[C@@H](C2CCCCC2)C(=O)OC2CCCC2)C=N1

Raloxifene 6-glucuronide Catalog No.:M13237-10 Hippo coactivator YAP1 upregulates SOX9Raloxifene 6 glucuronide is a primary metabolite of Raloxifene. Raloxifene 6 glucuronide is mediated mostly by UGT1A1 and UGT1A8. Raloxifene 6 glucuronide binds to estrogen receptor with an IC50 of 290 M. Raloxifene is a selective and nonsteroidal estrogen receptor modulator. Raloxifene activates TGF3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element containing vitellogenin promoter expression. Product

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