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Smiles: CN1CCN(CC1)C1=CC2=C(C(=C1)OCC(F)(F)F)C1=CN=C(C=C1N2C(C)C)NC1=CC=NC(=N1)C1C=NN(C=1)S(=O)(=O)C1CC1
Displays some inhibitory activity towards c-Kit
an abnormal enzyme produced by Philadelphia chromosomal translocation associated with chronic myeloid leukemia (CML)
is a potent CDK inhibitor
c-met-IN-1 60233 Smiles: CN1CCN(CC1)C1=CC2=C(C(=C1)OCC(F)(F)F)C1=CN=C(C=C1N2C(C)C)NC1=CC=NC(=N1)C1C=NN(C=1)S(=O)(=O)C1CC1c met IN 1 (compound 16) is a potent and selective c Met inhibitor, with IC50 of 1. 1 nM, with antitumor activity.. Product information CAS Number: 2084836 84 8 Molecular Weight: 640. 70 Formula: C35H37FN6O5 Chemical Name: N [3 fluoro 4 ({6 methoxy 7 [3 (4 methylpiperazin 1 yl)propoxy]quinolin 4 yl}oxy)phenyl] 1 (2 methoxyphenyl) 1H imidazole 4 carboxamide Smiles: CN1CCN(CCCOC2=CC3=NC=CC(OC4=CC=C(C=C4F)NC(=O)C4=CN(C=N4)C4=CC=CC=C4OC)=C3C=C2OC)CC1
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