AT-406 nbolone acetate COC1=CC2=C(NC3=CC(Br)=CC=C3)N=CN=C2C=C1OC

COC1=CC2=C(NC3=CC(Br)=CC=C3)N=CN=C2C=C1OC

It may slow progression of the clinical disease and delay the requirement for levodopa therapy

²⁸]triaconta-1(29)

CN(CCCC(C#N)(C(C)C)C1=CC(OC)=C(C=C1)OC)CCC1C=C(OC)C(=CC=1)OC

AT-406 nbolone acetate COC1=CC2=C(NC3=CC(Br)=CC=C3)N=CN=C2C=C1OCDeBio 1143, also known as AT 406, ARRY 334543and SM 406, is an orally bioavailable inhibitor of IAP (Inhibitor of Apoptosis Protein) family of proteins with potential apoptotic inducing and antineoplastic activity. AT 406 selectively inhibits the biological activity of IAP proteins, including X chromosome linked IAP (XIAP), the cellular IAPs 1 (c IAP1) and 2 (c IAP2) and melanoma inhibitor of apoptosis protein (ML IAP). This may restore and promote