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CAS Number: 1558021-37-6
It exhibits anti-proliferative effects on DU 145 cells independently of IGF-1 signaling (IC50 ~0
selective and cell-permeable inhibitor of histone demethylase JMJD2 (KDM4C)
and increases the pH
Thalidomide paverine hydrochloride CAS Number: 1558021-37-6Thalidomide is a synthetic derivative of glutamic acid (alpha phthalimido glutarimide) with teratogenic, immunomodulatory, anti inflammatory and anti angiogenic properties. Thalidomide acts primarily by inhibiting both the production of tumor necrosis factor alpha (TNF alpha) in stimulated peripheral monocytes and the activities of interleukins and interferons. This agent also inhibits polymorphonuclear chemotaxis and monocyte phagocytosis. In
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