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PD180970 indcues apoptosis of K562 leukemic cells
Solubility: DMSO 48 mg/mL (198
and this result persists during 14 days of the test
40S)-48-{[(2S
BW 246C 637CT018159 PD180970 indcues apoptosis of K562BW 246C is a DP receptor agonist. The prostaglandin D2 (PGD2) receptors, members of G protein coupled receptors, bind and are activated by prostaglandin D2. PGD2 receptors include the following proteins prostaglandin D2 receptor 1 (DP1) and prostaglandin D2 receptor 2 (DP2). In vitro: BW 246C was found to be the less active C 8 diastereomer of the DP receptor agonist its analog BW 245C, having 70 fold less activity than that of BW 245C. For BW 245C, a