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Chemical Name: 6-{imidazo[1
Identification of regions of the P2X(7) receptor that contribute to human and rat species differences in antagonist effects
Olsalazine is an anti-inflammatory drug used in the treatment of inflammatory bowel disease such as ulcerative colitis
tumor cell proliferation and metastasis
CP-466722 Size:Solid 10 mg Chemical Name: 6-{imidazo[1CP 466722 is an ATM inhibitor. CP466722 inhibited cellular ATM dependent phosphorylation events and disruption of ATM function resulted in characteristic cell cycle checkpoint defects. Inhibition of cellular ATM kinase activity was rapidly and completely reversed by removing CP466722. Interestingly, clonogenic survival assays showed that transient inhibition of ATM is sufficient to sensitize cells to IR and suggests that therapeutic radiosensitization