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Smiles: OC1(CC(=O)C2C=CC(=CC=2)C2CC2)C2=C(NC1=O)C(Cl)=CC=C2Cl
Chemical Name: 1-[(1R)-1-[1-(ethanesulfonyl)piperidin-4-yl]ethyl]-N-[(4-methoxy-6-methyl-2-oxo-1
718(1-3):383-92
without body weight loss and blood cell count decrease
KRA-533 Size:Contact [email protected] for quotation Smiles: OC1(CC(=O)C2C=CC(=CC=2)C2CC2)C2=C(NC1=O)C(Cl)=CC=C2ClKRA 533 is a potent KRAS agonist. KRA 533 binds to the GTP GDP binding pocket in the KRAS protein to prevent GTP cleavage, resulting in the accumulation of constitutively active GTP bound KRAS that triggers both apoptotic and autophagic cell death pathways in cancer cells. Product information CAS Number: 10161 87 2 Molecular Weight: 314. 18 Formula: C13H16BrNO3 Chemical Name: 4 [4 (2 bromoacetamido)butyl]benzoic acid Smiles:
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