SU14813 maleate - CAS# 849643-15-8 Size:Solid 10 mg Formula: C22H26FN5O6

Name: SU14813 maleate - CAS# 849643-15-8 Size:Solid 10 mg Formula: C22H26FN5O6
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SKU: 28581521876
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SKU: 28581521876

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Description

Formula: C22H26FN5O6

CAS Number: 331963-29-2

It has minimal inhibition of UCHL-1

2014 Mar 18

SU14813 maleate - CAS# 849643-15-8 Size:Solid 10 mg Formula: C22H26FN5O6SU14813 is an oral, multitargeted tyrosine kinase inhibitor (TKI) targeting vascular endothelial growth factor receptors (VEGFR), platelet derived growth factor receptors (PDGFR), KIT, and fms like tyrosine kinase 3 (FLT 3) (1). SU14813 was developed as a next generation TKI agent following sunitinib (SU11248) designed to demonstrate optimized pharmacokinetic (PK) and tolerability profiles. SU14813 demonstrated broad and potent antitumor activity

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