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BLU-9931 is exquisitely selective for FGFR4 versus other FGFR family members and all other kinases
56(22):9251-64
Drenckhan M
JNJ 63533054
OSI-930 penem monohydrate BLU-9931 is exquisitely selective forOSI 930 is a selective thiophene derived tyrosine kinase inhibitor with potential antineoplastic activity. Tyrosine kinase inhibitor OSI 930 inhibits stem cell factor receptor (c Kit) and the vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of both tumor cell proliferation and tumor angiogenesis. Both c Kit and VEGFR2 are overexpressed in a variety of cancers. Check for active clinical trials or closed
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