Rebaudioside A desartan Cilexetil-d5 3-dihydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]acetamide

3-dihydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]acetamide

Formula: C15H10F6N2O3

CID 11502183

Chemical Name: 2-bromo-N-[2-(2

Rebaudioside A desartan Cilexetil-d5 3-dihydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]acetamideRebaudioside A is a steviol glycoside, glucosidase inhibitor with IC50 of 35. 01 g ml. can inhibit ATP sensitive K+ channels. Target: glucosidase IC 50: 35. 01 ug mLIn vitro: rebaudioside A stimulat the insulin secretion from MIN6 cells in a dose and glucose dependent manner. In conclusion, the insulinotropic effect of rebaudioside A is mediated via inhibition of ATP sensitive K+ channels and requires the presence of high glucose. In vivo: in vivo