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Cdk7 from Cdk7as/as or Cdk7+/+ cells is immunoprecipitated and tested its kinase activity towards both a Pol II CTD-containing fusion protein (GST-CTD) and human Cdk2
KUN79359 (15 μM
72C:243-253
YC-1 is widely used as a potent inhibitor of HIF-1alpha both in vitro and in vivo
SDZ 220-581 - CAS# 174575-17-8 ir mesylate Cdk7 from Cdk7as/as or Cdk7+/+SDZ 220 581 is a potent, competitive antagonist at the NMDA glutamate receptor subtype, reversed haloperidol induced catalepsy in rats, a widely used model of Parkinson's disease. Product information CAS Number: 174575 17 8 Molecular Weight: 369. 74 Formula: C16H17ClNO5P Synonym: SDZ 220 581 Chemical Name: (2S) 2 amino 3 [2' chloro 5 (phosphonomethyl) [1,1' biphenyl] 3 yl]propanoic acid Smiles: N[C@@H](CC1=CC(=CC(CP(O)(O)=O)=C1)C1=CC=CC=C1Cl)C(O)=O