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Formula: C16H24N10O4
Portelius E
InChiKey: PBCZSGKMGDDXIJ-NXNPIKFHSA-N
29)27-11-9-22-10-12-27/h7-8
BMS-986251 Catalog No.:M33163-C Formula: C16H24N10O4BMS 986251 is an orally active and selective RORt inverse agonist with an EC50 of 12 nM for RORt GAL4. BMS 986251 inhibits IL 17 with an EC50 of 24 nM in human whole blood assay. BMS 986251 demonstrates robust efficacy in mouse acanthosis and Imiquimod induced (HY B0180) models (preclinical models of psoriasis). Product information CAS Number: 2460133 35 9 Molecular Weight: 667. 61 Formula: C30H29F8NO5S Chemical Name: (1R,3S,4R) 4 [(3aR,9bR) 9b (4