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Sadowski M
CID 49852229
InChiKey: PIAFFJUUNXEDEW-PXPMWPIZSA-N
treatment with emixustat during the period of ischemia and reperfusion injury produces a 30%reduction in retinal neovascularization (ED50=0
GSK484 hydrochloride ty H Sadowski MGSK484 hydrochloride is a selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor. GSK484 hydrochloride demonstrates high affinity binding to PAD4 with IC50s of 50 nM in the absence of Calcium. In the presence of 2 mM Calcium, notably lower potency (250 nM) is observed. Product information CAS Number: 1652591 81 5 Molecular Weight: 510. 03 Formula: C27H32ClN5O3 Chemical Name: (3S,4R) 3 amino 1 {2 [1 (cyclopropylmethyl) 1H indol 2 yl] 7
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