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CU-3 aflumizone CAS Number: 38183-12-9

SKU: 81750575853

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Description

CAS Number: 38183-12-9

Dp44mT is cytotoxic to breast cancer cells

PF-4989216 inhibits human colon carcinoma S1 cell line and ABCG2-overexpressing subline S1-M1-80 with IC50s of 1

4-dihydronaphthalen-2-yl)sulfanyl]propanoic acid

CU-3 aflumizone CAS Number: 38183-12-9CU 3 is the racemate of (5Z,2E) CU 3. (5Z,2E) CU 3 is a potent and selective inhibitor against the isozyme of DGK with an IC50 value of 0. 6 M, competitively inhibits the affinity of DGK for ATP with a Km value of 0. 48 mM. (5Z,2E) CU 3 targets the catalytic region, but not the regulatory region of DGK. (5Z,2E) CU 3 has antitumoral and proimmunogenic effects, enhances the apoptosis of cancer cells and the activation of T cells. Product information CAS

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